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52 , e12546 (2019)

In the presence of thiol compounds such as glutathione or cysteine, dopaquinone is diverted toward the synthesis of pheomelanin a lighter, yellow-to-reddish pigment instead of the darker, brown-to-black eumelanin that forms when thiols are absent

It indicates that this drug can cause withdrawals, suicidal thoughts, and suicidal behaviors

Examples are cysteine supplements in the form of whey or N -acetylcysteine, antioxidant vitamins (B,C,E), alpha-lipoic acid, selenium or phytonutrients (i.e., Brassica vegetables and green tea) (25)

[5] Vitamin B 12 is the most chemically complex of all vitamins, [2] [6] [7] and is synthesized exclusively by certain archaea and bacteria