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The reduction in cartilage type II collagen synthesis in early RA may contribute to the developing pathology, since a lack of synthesis of this molecule would inhibit maintenance of cartilage matrix

doi: 10.1016/j.nut.2015.05.006 49 BennettBJde Aguiar VallimTQWangZShihDMMengYGregoryJet al

This stacking often causes problems even when each individual product would be well-tolerated alone