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Keap1: one stone kills three birds Nrf 2, IKK and Bcl-2/Bcl-xL

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Furthermore, Fer-1 mitigates oxidative stress by downregulating prostaglandin endoperoxide synthase 2 while upregulating GPX4 and Nrf2, thereby decreasing lipid peroxidation (115)

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The role of AI in accelerating drug development, advancing human longevity, and overcoming biological limitations [2:19:45]

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doi: 10.1186/s13395-025-00375-5

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