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Some individuals with inherited deficiencies of specific enzymes that synthesise glutathione may develop neurological complications later in life 22

The dose of NAC ranged from 600 to 3000 mg/day

Werner syndrome (WS), which is distinguished by severe metabolic dysfunction, dyslipidemia, early atherosclerosis, and insulin resistance diabetes, is thought to most closely mimic normal aging

Resolution of pyroglutamic acidosis occurred after discontinuation of APAP