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Dietary deficiency: Vegans (strict vegetarians who do not eat any meat, fish, egg, or dairy products) can develop vitamin B 12 deficiency because they lack vitamin B 12 in their diets

Variation of glucoraphanin metabolism in vivo and ex vivo by human gut bacteria

This recognition initiates downstream signaling cascades, amplifying a localized microbial imbalance into a systemic inflammatory state 143

Dysbiosis is an imbalance in gut microbiota in which key beneficial (commensal) species become overrun by less favorable and/or more inflammatory bacteria or other microorganisms

Cycle Length: Can last for several months, often ranging from 3 to 6 months or more, depending on individual goals and response