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"These findings add to a growing body of evidence suggesting that chronic or problematic cannabis use may contribute to cancer risk in tissues exposed to combustion products." By analyzing the electronic health records from over 45,000 patients, of whom 949 developed CUD, Cuomo found: After adjusting for age, sex, body mass index and smoking status, people had a 325 percent times higher likelihood of contracting oral cancer within five years compared to those without CUD