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NF-kappaB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS
What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug
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A case-control study involving 4,995 cancer patients and 4,972 controls from a Chinese population found that a variant in the Caspase-8 gene was associated with reduced susceptibility to several cancers, including lung, esophageal, gastric, colorectal, cervical, and breast cancers
192 LiuT.ZhangL.JooD.SunS.-C
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