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Furthermore, it can lead to impaired quality of life, infertility, and an increased risk of pregnancy-related hypertensive disorders, as well as adverse obstetric and neonatal outcomes

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A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)

Polyak, C.Gamberi, Cyst Reduction by Melatonin in a Novel Drosophila Model of Polycystic Kidney Disease

No FDA approval for medical use