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The Bruner-style incision was centered over the fourth web space, extending distally from Kaplans cardinal line to the proximal palmar wrist crease

The estimated mean change in body weight at week 68 was 20.4% with CagriSema versus 3.0% with placebo (a difference of about 17 percentage points), and more CagriSema participants reached weight-loss thresholds of 5%, 20%, 25%, and 30% than placebo

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