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Patients with controlled uric acid level and doing well on allopurinol would seem to have no reason to switch to this new agent, in view of allopurinol's lower cost and 40-year history of an overall very good safety record (see "Allopurinol" discussion above)

Chronically elevated insulin, visceral fat, systemic inflammation, and oxidative stress are deeply intertwined with the hallmarks of aging (like cellular senescence and mitochondrial dysfunction)

The Bottom Line: Those who still want to try methylene blue should first talk to a clinician to ensure they're not at risk for adverse side effects

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Testosterone replacement therapy (TRT) is for men diagnosed with low testosterone based on blood testing and clinical symptoms