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While both serum creatinine, cystatin C, eGFRs, and mGFRs (by creatinine, inulin, iothalamate) all have relatively large and proportionately similar reference ranges [8,9], the within-individual variations for serum creatinine, cystatin C, and eGFR are much lower than for mGFR by creatinine clearance [5,10], or by iothalamate and inulin methods [7,11]

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Phase 3: Optimize both (weeks 9-16) Increase AOD 9604 to 300-500mcg daily based on tolerance

Kazemi et al