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Food and Drug Administration (FDA) for cosmetic use

The clinically significant long-term concern is glucose metabolism

An ishchemic-reperfusion model was used by Bloomer, Smith, and Fisher-Wellman to examine blood nitrite/nitrate levels as an indication of NO production [13]

You can read more about the studies and research conducted by the Volunteer Fire Foundation and the Integrative Healers Action Network as well as the board's presentation on compounding.