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Apart from these, other factors are also implicated such as phototoxic drugs, anticonvulsant medications, and certain cosmetics.[] Melasma is resistant to treatment and has a high rate of recurrence

Firstly , the premixed cartridge removes the need for manual preparation, allowing researchers to focus on controlled experimental procedures while saving valuable laboratory time

At the same time, studies in vitro have shown that L-carnitine inhibits the activity of matrix metalloproteinases MMP-1 and MMP-2, enzymes that contribute to the degradation of the dermal matrix under oxidative stress

This study was approved by the research ethics board at each site (Conjoint Health Research Ethics Board at the University of Calgary, REB152296