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Previous work has shown that the abundance of Lactobacillus reuteri (normalized to a control group) decreases during the onset of obesity and remains suppressed even after dieting in mice 99 , which parallels our observations that vehicle-treated diet-switched mice had lower levels of Lactobacillus than the 5A-1MQ-treated mice, the latter of which also demonstrated greater weight loss

So that's like two months of episodes or even five and five

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Temperature proves the dominant factor affecting degradation rates - every 10C increase doubles degradation speed, making refrigeration at 2-8C essential for all reconstituted solutions and beneficial for extending powder shelf life beyond basic 12-18 month refrigerated baseline

And that, in the world of research, is everything