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The cystine/GSH/GPX4 system is a conventional method for inhibiting iron removal, with system Xc-, being vital for the production of GSH, a key antioxidant defence route [78]

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Akkermansia muciniphila and its outer protein Amuc_1100 regulates tryptophan metabolism in colitis

structureactivity relationship studies showed that electrondonating groups and small alkyl chains between the active scaffolds can be beneficial for inhibiting the XO enzyme