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Participants with moderate depression and elevated inflammatory biomarkers, such as high-sensitivity C-reactive protein, IL-6, or TNF-, would be enrolled to target an inflammation-positive depressive phenotype

The effect of riboflavin supplementation on the systemic redox status in healthy volunteers: a post-hoc analysis of the RIBOGUT trial

Agarose gels were all 1.5% w/v agarose stained with ethidium bromide (Fischer) and imaged on BioRad GelDoc imager

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notably, the MMP-2 effect was reproduced by copper ions but not by the peptide alone, whereas the broader matrix-synthesis effects require the intact tripeptide