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[4], Thomas et al

Despite substantial progress in understanding the therapeutic potential of EVs, the mechanisms underlying their regulation of intercellular metabolism remain incompletely elucidated

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Preclinical research suggests BPC-157 may support tendon, ligament, and joint tissue healing, but controlled canine clinical trials remain limited

Therefore the overall impact on fertility that ROS has is not a matter of if it is there or not (as mentioned earlier, some oxidative stress is required for various reproductive physiological functions), but when levels of ROS are too high (or antioxidant levels are too low) it becomes pathological to sperm and the ability to get pregnant