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It is found in every cell of the body and serves as the first line of defense, with particularly high levels in the liver, kidneys, lungs, adrenal glands, reproductive organs, brain and pancreas

fermentum LM1016 reduces inflammatory signaling in the intestinal tract, we further performed transcriptome analysis in colonic tissues

Mechanistically, the thioredoxin interacting protein (TXNIP) serves as a link between cellular redox state and NLRP3 activation