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Unlike GLP-1 peptides like semaglutide , which frequently cause significant nausea as part of their mechanism of action, AOD 9604 does not suppress appetite or slow gastric emptying

Evidence for involvement of the transcription factor Egr-1

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While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

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