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Arunachalam PS, Wimmers F, Mok CKP, Perera RAPM, Scott M, Hagan T, Sigal N, Feng Y, Bristow L, Tak-Yin Tsang O, Wagh D, Coller J, Pellegrini KL, Kazmin D, Alaaeddine G, Leung WS, Chan JMC, Chik TSH, Choi CYC, Huerta C, Paine McCullough M, Lv H, Anderson E, Edupuganti S, Upadhyay AA, Bosinger SE, Maecker HT, Khatri P, Rouphael N, Peiris M, Pulendran B (2020) Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Thus, these findings suggested that ferroptosis regulation in the setting of NAFLD is a promising possibility as a novel therapeutic target that merits further evaluation

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Altogether, by enabling the TCA cycle, Fe-S clusters take part in the controlled combustion of nutrients and supply metabolic precursors for nucleotide, lipid, and protein biogenesis