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Bioluminescence For in vivo luminescence, mice were injected i.p

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6 Coincidentally, downregulated Sirtuin 3 (Sirt3)-mediated hyperacetylation of PDHA1 promotes the lactylation of mitochondrial fission 1 protein (Fis1) at K20 by increasing lactate overproduction in renal tubular epithelial cells, resulting in excessive mitochondrial injury

4.2 Ferroptosis and AKI AKI has always been a severely debilitating disease worldwide, and it remains a focus of clinical research (146)