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Engaging in regular resistance exercise and maintaining adequate dietary protein intake are generally recommended alongside any weight-loss intervention to help preserve lean mass consistent with NICE obesity management guidance (CG189)

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Safety of Cagrinlitide and CagriSema In the obesity trial, the proportions of participants who discontinued study treatment due to adverse events were 2-6Percentage, 7Percentage, and 3Percentage in the cagrilintide, liraglutide and placebo groups, respectively [9]

Note on humans: Kisspeptin remains investigational it is not approved for human treatment, and large-scale efficacy is not established [13]