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Professor Edmund Rolls, from the Institute of Science and Technology for Brain-Inspired Intelligence, comments, These discoveries help to demonstrate that there are different neural bases of different types of addiction, and that the orbitofrontal cortex, a key brain region in emotion, is implicated in these two types of addiction. Professor Jianfeng Feng, from the Institute of Science and Technology for Brain-Inspired Intelligence comments, These findings could have important public health implications, as both drinking and smoking affect a large population worldwide