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References Isotretinoin and intestinal inflammation: what gastroenterologists need to know Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin Isotretinoin and Hepatotoxicity in Patients with Acne: A Narrative Review Isotretinoin treatment induces oxidative toxicity in blood of patients with acne vulgaris

The PM size fraction greatly influences PM health effects, owing to their varying ability to penetrate different parts of the respiratory system 8

Individual needs vary

EVIDENCE GRADES Lau 2021 Lancet dose-dependent placebo-subtracted weight loss to ~10.8% at 26 weeks